The immune system consists of organs and cells within the human body. The bone marrow produces  B cells, granulocytes, immature thymocytes, natural killer cells and red blood cells and platelets. It is the process of hematopoiesis that bone marrow stem cells either become mature cells within the immune system or develop into maturation outside of the immune system. For example immature thymocytes migrate into the thymus and produce mature T cells. The spleen creates a immunologic filter for the body's blood. It consists of B and T cells, macrophages, dendritic cells, natural killer cells and red blood cells. The spleen also destroys old red blood calls and is responsible for producing antibodies. The human body not only contains blood it also contains fluid. The lymph nodes are the body's immunologic filter for the lymph fluid that is produced. They are responsible for draining fluid from tissue in our bodies. This is also where antigens are filtered out. The lymph nodes contain the same type of cells as the spleen.

The cells of the immune system consist of the T lymphocytes that include not only the T cell but a T cell helper called CD4. Both the T cell and helper cell help fight off infection and produce immune responses. Another type of T-cell is called the CD8 cell, which is responsible for killing tumor and viral cells, parasites and also be eliminated by the CD8 cell. NK cells or natural killer cells kill off lymphomas and melanomas. B cells or B lymphocytes are responsible for antibodies that are produced in response to bacteria, viruses and tumors. Granulocytes or polymorphonuclear or PMN leukocytes, which are white blood cells these cells also remove bacteria and parasites from the body. Macrophages are responsible for the regulation of immune responses, they provide antigen/antibody response to B and T cells.

The Dendritic cells originates in the bone marrow. They present to B or T cells for antigen/antibody response and are found in the thymus, spleen and lymph nodes, they are also located in other areas of the body. APC cells or antigen presenting cells are either Macrophage or Dendritic cells. They usually present themselves to either B or T cells this will enable antigens to be produced from either the B or T cells that will ultimately kill off bacteria, viruses, tumors, ect.. This is crucial in that the Macrophage or Dendritic cells are the informant cells that dime to the B or T cells, so that antibodies will know that they have to be produced to eliminate and virus or bacteria. If the body is unable to signal to the B or T cells or any one of their helper or killer cells it will be unable to defend itself against illness. 

There is a saying..
What your mother doesn't know won't hurt.  To somewhat apply this in context to cells and their much needed informers to let them know when the onslaught of war is present. Mother cells or those cells that produce antibodies in the body's defense need to be aware of illness in the body.  If the body lacked the signal or transmission of information from Macrophages or Dendrites then it would be unable to defend itself. Illness could have an onset in a person and then spread rapidly before the body's own defense or that of the nature of medicine would be able to assist the person in getting the medical help needed.

Dendrites and macrophages contain the CCR5 protein which is a G protein-coupled receptor. Harmful viruses bind themselves to this protein and thus affect such antigen/antibody responses when presented to the B, T, CD4, CD8 and killer cells for antibody production to fight off infection. Dendritic cells are present in skin and mucosa. These cells are called Langerhans cells and are also found in the lining of the nose, intestines and lungs. Since the Dendritic cells have external contact with that of the environment it may be possible that the spread of harmful chemicals, air and other toxins could possibly invade such cells causing them to become compromised as antigen/antibody presenting cells.

Supplements from mother nature could possibly help with bone marrow and Dendritic cells when they are in need of restoration due to the environment and other factors affecting one's health.  Astragalus, Echinacea, Reishi Mushroom Extract, Tumeric including many others are supplements that can be used for bone marrow disorders and overall health.

When your mother does know and refuses to do absolutely nothing about it is probably the same as when she does know and did something about it. I mean who would you rather be punished by your own mother, some stank of a person who really does not know you very much at all, the neighborhood or the almighty?